Thymosin beta-4 fragment8 min read

TB-500: What It Is and the Research

A neutral, source-cited overview of TB-500 for qualified and independent researchers — what it is, the areas the published literature has studied, and where to find the primary sources.

VNG Research TeamJuly 15, 2026
Class
Thymosin beta-4 fragment
Published studies cited
10
Literature span
2007–2023

For research & educational purposes only. This article is a neutral, procedural reference for laboratory / in-vitro research handling — not medical advice or a usage recommendation. These materials are not for human or animal consumption.

On this page

What TB-500 is

TB-500 is a synthetic peptide corresponding to an active fragment of the naturally occurring protein Thymosin Beta-4. It is supplied as an analytical-grade reference material for laboratory research.

What the research has examined

Published studies have examined thymosin beta-4 and its fragments in tissue-repair, cell-migration, and angiogenesis research models.

Listing an area of study is not a claim about any product or outcome. These references are provided so qualified researchers can locate the primary literature. All materials are supplied for laboratory research use only.

Reconstitution reference

Standard laboratory reconstitution volumes for TB-500, from the VNG Reconstitution Sheet. See the full reconstitution guide for the method and concentration math.

ProductVialBacteriostatic waterResulting concentration
TB-50010 mg2 mL5 mg/mL
GLOW (GHK-Cu + BPC-157 + TB-500)70 mg3 mL~23.3 mg/mL
KLOW (BPC-157 + GHK-Cu + TB-500 + KPV)80 mg3 mL~26.7 mg/mL

Published research

A selection of peer-reviewed and clinical literature indexed on PubMed. Provided so qualified researchers can locate the primary sources — inclusion here is not a claim about any product or outcome.

  1. Peer-reviewed studyAnnals of the New York Academy of Sciences · 2007

    Beta-thymosins — overview

    View on PubMed
  2. Peer-reviewed studyInternational immunopharmacology · 2023

    Thymosin beta-4 in regenerative therapy research

    View on PubMed
  3. Peer-reviewed studyExpert opinion on biological therapy · 2018

    Thymosin beta-4 and the eye

    View on PubMed
  4. Peer-reviewed studyCurrent medicinal chemistry · 2020

    Thymosin beta-4 and tissue repair in heart injury

    View on PubMed
  5. Lab / formulation studyVitamins and hormones · 2016

    Thymosin beta-4 and liver (hepatic stellate) cells

    View on PubMed
  6. Peer-reviewed studyAnnals of the New York Academy of Sciences · 2010

    Thymosin beta-4 tissue-repair peptide — animal studies

    View on PubMed
  7. Animal-model studyInternational immunopharmacology · 2023

    Thymosin beta-4 and bacterial keratitis

    View on PubMed
  8. Animal-model studyKidney international · 2016

    Thymosin beta-4 and kidney (glomerular) disease

    View on PubMed
  9. Peer-reviewed studyBrain : a journal of neurology · 2014

    Thymosin beta-4 in glioblastoma research

    View on PubMed
  10. Animal-model studyInternational immunopharmacology · 2023

    Thymosin beta-4 and middle-ear healing

    View on PubMed

References & resources

Related reference materials

VNG Research Team

VNG Labs supplies analytical-grade reference materials with lot-matched Certificates of Analysis. Our write-ups are neutral, source-cited references for qualified and independent researchers.

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Research use only. Not for human consumption or veterinary use. Sold exclusively to qualified researchers for in vitro and laboratory research. These statements have not been evaluated by the FDA. Not intended to diagnose, treat, cure, or prevent any disease. Refrigerate upon receipt. Keep in dark environment.