For research & educational purposes only. This article is a neutral, procedural reference for laboratory / in-vitro research handling — not medical advice or a usage recommendation. These materials are not for human or animal consumption.
What MOTS-c is
MOTS-c is a mitochondrial-derived peptide encoded within the mitochondrial genome. It is supplied as an analytical-grade reference material for laboratory research.
What the research has examined
Published research has investigated MOTS-c in metabolic-regulation and cellular-stress-response contexts, largely in animal and cell models.
Listing an area of study is not a claim about any product or outcome. These references are provided so qualified researchers can locate the primary literature. All materials are supplied for laboratory research use only.
Reconstitution reference
Standard laboratory reconstitution volumes for MOTS-c, from the VNG Reconstitution Sheet. See the full reconstitution guide for the method and concentration math.
| Product | Vial | Bacteriostatic water | Resulting concentration |
|---|---|---|---|
| MOTS-c | 10 mg | 0.5 mL | 20 mg/mL |
| MOTS-c | 40 mg | 2 mL | 20 mg/mL |
Published research
A selection of peer-reviewed and clinical literature indexed on PubMed. Provided so qualified researchers can locate the primary sources — inclusion here is not a claim about any product or outcome.
- Mechanistic studyMetabolites · 2023
MOTS-c and metabolic disorders
View on PubMed - Mechanistic studyAmerican journal of physiology. Endocrinology and metabolism · 2021
MOTS-c and muscle-atrophy signaling
View on PubMed - Mechanistic studyFrontiers in endocrinology · 2023
MOTS-c mitochondrial peptide — therapeutic overview
View on PubMed - Mechanistic studyBioEssays : news and reviews in molecular, cellular and developmental biology · 2019
MOTS-c as a mitochondrial regulator of the nucleus
View on PubMed - Mechanistic studyCell metabolism · 2015
MOTS-c, metabolism & insulin resistance
View on PubMed - Mechanistic studyAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
MOTS-c and ovarian cancer — mechanism study
View on PubMed - Peer-reviewed studyMitochondrion · 2023
MOTS-c and pulmonary fibrosis
View on PubMed - Mechanistic studyPharmacological research · 2022
MOTS-c and gestational diabetes
View on PubMed - Mechanistic studyFrontiers in physiology · 2023
MOTS-c and bone metabolism
View on PubMed - Human clinical studyInternational journal of molecular sciences · 2022
MOTS-c in aging and age-related disease
View on PubMed
References & resources
Related reference materials
VNG Research Team
VNG Labs supplies analytical-grade reference materials with lot-matched Certificates of Analysis. Our write-ups are neutral, source-cited references for qualified and independent researchers.
More from the research blogResearch use only. Not for human consumption or veterinary use. Sold exclusively to qualified researchers for in vitro and laboratory research. These statements have not been evaluated by the FDA. Not intended to diagnose, treat, cure, or prevent any disease. Refrigerate upon receipt. Keep in dark environment.
