For research & educational purposes only. This article is a neutral, procedural reference for laboratory / in-vitro research handling — not medical advice or a usage recommendation. These materials are not for human or animal consumption.
What Melanotan I is
Melanotan I (afamelanotide) is a synthetic analog of alpha-melanocyte-stimulating hormone (α-MSH). It is supplied as an analytical-grade reference material for laboratory research.
What the research has examined
Published research has studied melanocortin analogs in the context of melanin/pigmentation biology and photoprotection models.
Listing an area of study is not a claim about any product or outcome. These references are provided so qualified researchers can locate the primary literature. All materials are supplied for laboratory research use only.
Reconstitution reference
Standard laboratory reconstitution volumes for Melanotan I, from the VNG Reconstitution Sheet. See the full reconstitution guide for the method and concentration math.
| Product | Vial | Bacteriostatic water | Resulting concentration |
|---|---|---|---|
| Melanotan I | 10 mg | 2 mL | 5 mg/mL |
| Melanotan II | 10 mg | 2 mL | 5 mg/mL |
Published research
A selection of peer-reviewed and clinical literature indexed on PubMed. Provided so qualified researchers can locate the primary sources — inclusion here is not a claim about any product or outcome.
- Peer-reviewed study · 2012
Afamelanotide — overview
View on PubMed - Mechanistic studyNature reviews. Endocrinology · 2023
Melanocortin system and metabolic disorders
View on PubMed - Peer-reviewed reviewPostepy dermatologii i alergologii · 2024
Afamelanotide in skin disease — review
View on PubMed - Peer-reviewed studyArchives of dermatological research · 2019
Acne pathogenesis and anti-acne agents
View on PubMed - Peer-reviewed studyExpert review of clinical pharmacology · 2021
Afamelanotide and phototoxicity in protoporphyria
View on PubMed - Peer-reviewed reviewAmerican journal of clinical dermatology · 2016
Afamelanotide in protoporphyria — review
View on PubMed - Peer-reviewed reviewJournal of drugs in dermatology : JDD · 2021
Afamelanotide — dermatology applications review
View on PubMed - Peer-reviewed studyThe New England journal of medicine · 2015
Afamelanotide for protoporphyria — NEJM
View on PubMed - Human clinical studyClinical pharmacokinetics · 2017
Afamelanotide pharmacokinetics & clinical use
View on PubMed - Peer-reviewed studyExpert review of clinical pharmacology · 2015
Afamelanotide and dermal phototoxicity
View on PubMed
References & resources
Related reference materials
VNG Research Team
VNG Labs supplies analytical-grade reference materials with lot-matched Certificates of Analysis. Our write-ups are neutral, source-cited references for qualified and independent researchers.
More from the research blogResearch use only. Not for human consumption or veterinary use. Sold exclusively to qualified researchers for in vitro and laboratory research. These statements have not been evaluated by the FDA. Not intended to diagnose, treat, cure, or prevent any disease. Refrigerate upon receipt. Keep in dark environment.
