For research & educational purposes only. This article is a neutral, procedural reference for laboratory / in-vitro research handling — not medical advice or a usage recommendation. These materials are not for human or animal consumption.
What KPV is
KPV is a tripeptide (lysine-proline-valine) corresponding to the C-terminal fragment of alpha-MSH. It is supplied as an analytical-grade reference material for laboratory research.
What the research has examined
Research has investigated KPV in the context of anti-inflammatory signaling pathways in cell and animal models.
Listing an area of study is not a claim about any product or outcome. These references are provided so qualified researchers can locate the primary literature. All materials are supplied for laboratory research use only.
Reconstitution reference
Standard laboratory reconstitution volumes for KPV, from the VNG Reconstitution Sheet. See the full reconstitution guide for the method and concentration math.
| Product | Vial | Bacteriostatic water | Resulting concentration |
|---|---|---|---|
| KPV | 10 mg | 2 mL | 5 mg/mL |
| KLOW (BPC-157 + GHK-Cu + TB-500 + KPV) | 80 mg | 3 mL | ~26.7 mg/mL |
Published research
A selection of peer-reviewed and clinical literature indexed on PubMed. Provided so qualified researchers can locate the primary sources — inclusion here is not a claim about any product or outcome.
- Animal-model studyInflammatory bowel diseases · 2008
KPV tripeptide and inflammatory bowel disease — animal model
View on PubMed - Animal-model studyBiomaterials science · 2021
KPV hydrogel and oral mucositis
View on PubMed - Peer-reviewed studyAdvances in experimental medicine and biology · 2010
Anti-inflammatory effects of α-MSH-related peptides
View on PubMed - Peer-reviewed studyGastroenterology · 2008
KPV tripeptide and intestinal inflammation
View on PubMed - Lab / formulation studyMolecular therapy : the journal of the American Society of Gene Therapy · 2017
KPV nanoparticle delivery and ulcerative colitis
View on PubMed - Animal-model studyGastroenterology · 2010
Colon-targeted nanoparticle delivery and colitis — mouse model
View on PubMed - Animal-model studyACS biomaterials science & engineering · 2021
KPV-stabilizing hydrogel and ulcerative colitis — rats
View on PubMed - Animal-model studyCellular and molecular gastroenterology and hepatology · 2016
PepT1 and KPV tripeptide in colitis-associated cancer — mouse
View on PubMed - Peer-reviewed studyPloS one · 2018
Structural modification of the KPV tripeptide
View on PubMed - Peer-reviewed studyExperimental eye research · 2006
α-MSH tripeptide and corneal wound healing
View on PubMed
References & resources
Related reference materials
VNG Research Team
VNG Labs supplies analytical-grade reference materials with lot-matched Certificates of Analysis. Our write-ups are neutral, source-cited references for qualified and independent researchers.
More from the research blogResearch use only. Not for human consumption or veterinary use. Sold exclusively to qualified researchers for in vitro and laboratory research. These statements have not been evaluated by the FDA. Not intended to diagnose, treat, cure, or prevent any disease. Refrigerate upon receipt. Keep in dark environment.