Synthetic peptide analog8 min read

GLP-3 (RT): What It Is and the Research

A neutral, source-cited overview of GLP-3 (RT) for qualified and independent researchers — what it is, the areas the published literature has studied, and where to find the primary sources.

VNG Research TeamJuly 15, 2026
Class
Synthetic peptide analog
Published studies cited
10
Literature span
2023–2026

For research & educational purposes only. This article is a neutral, procedural reference for laboratory / in-vitro research handling — not medical advice or a usage recommendation. These materials are not for human or animal consumption.

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What GLP-3 (RT) is

Retatrutide (research code LY3437943), sometimes referred to as GLP-3, is an investigational triple-hormone receptor agonist that acts on the GLP-1, GIP, and glucagon receptors. It is supplied as an analytical-grade reference material for laboratory research.

What the research has examined

Published research has examined retatrutide primarily in metabolic-science contexts, including clinical trials measuring changes in body weight and metabolic markers.

Listing an area of study is not a claim about any product or outcome. These references are provided so qualified researchers can locate the primary literature. All materials are supplied for laboratory research use only.

Reconstitution reference

Standard laboratory reconstitution volumes for GLP-3 (RT), from the VNG Reconstitution Sheet. See the full reconstitution guide for the method and concentration math.

ProductVialBacteriostatic waterResulting concentration
Retatrutide (GLP-3)5 mg0.5 mL10 mg/mL
Retatrutide (GLP-3)10 mg1 mL10 mg/mL
Retatrutide (GLP-3)20 mg2 mL10 mg/mL
Retatrutide (GLP-3)30 mg3 mL10 mg/mL

Published research

A selection of peer-reviewed and clinical literature indexed on PubMed. Provided so qualified researchers can locate the primary sources — inclusion here is not a claim about any product or outcome.

  1. Human clinical studyThe New England journal of medicine · 2023

    Retatrutide for obesity — Phase 2 trial

    View on PubMed
  2. Peer-reviewed studyBiomolecules · 2025

    Retatrutide in obesity pharmacotherapy

    View on PubMed
  3. Peer-reviewed studyEuropean journal of pharmacology · 2024

    Retatrutide in obesity and diabetes therapy

    View on PubMed
  4. Human clinical studyLancet (London, England) · 2023

    Retatrutide for type 2 diabetes — Phase 2 trial

    View on PubMed
  5. Human clinical studyNature medicine · 2024

    Retatrutide for fatty liver disease — Phase 2a trial

    View on PubMed
  6. Systematic review of trialsProceedings (Baylor University. Medical Center) · 2025

    Retatrutide for obesity — systematic review & meta-analysis

    View on PubMed
  7. Systematic review of trialsMetabolism open · 2024

    Retatrutide on weight & metabolic markers — meta-analysis

    View on PubMed
  8. Human clinical studyDiabetes, obesity & metabolism · 2026

    Retatrutide — TRIUMPH clinical trial program

    View on PubMed
  9. Human clinical studyThe lancet. Diabetes & endocrinology · 2025

    Retatrutide and body composition in type 2 diabetes — Phase 2

    View on PubMed
  10. Systematic review of trialsJournal of basic and clinical physiology and pharmacology · 2025

    Retatrutide for obesity — review of clinical trials

    View on PubMed

References & resources

Related reference materials

VNG Research Team

VNG Labs supplies analytical-grade reference materials with lot-matched Certificates of Analysis. Our write-ups are neutral, source-cited references for qualified and independent researchers.

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Research use only. Not for human consumption or veterinary use. Sold exclusively to qualified researchers for in vitro and laboratory research. These statements have not been evaluated by the FDA. Not intended to diagnose, treat, cure, or prevent any disease. Refrigerate upon receipt. Keep in dark environment.