For research & educational purposes only. This article is a neutral, procedural reference for laboratory / in-vitro research handling — not medical advice or a usage recommendation. These materials are not for human or animal consumption.
What GHK-Cu is
GHK-Cu is a naturally occurring copper-binding tripeptide (glycyl-L-histidyl-L-lysine complexed with copper) first isolated from human plasma. It is supplied as an analytical-grade reference material for laboratory research.
What the research has examined
GHK-Cu is one of the more extensively studied peptides in the literature, with research spanning skin and cosmetic science, wound-healing models, and gene-expression studies.
Listing an area of study is not a claim about any product or outcome. These references are provided so qualified researchers can locate the primary literature. All materials are supplied for laboratory research use only.
Reconstitution reference
Standard laboratory reconstitution volumes for GHK-Cu, from the VNG Reconstitution Sheet. See the full reconstitution guide for the method and concentration math.
| Product | Vial | Bacteriostatic water | Resulting concentration |
|---|---|---|---|
| GHK-Cu | 50 mg | 1.5 mL | ~33.3 mg/mL |
| GHK-Cu | 100 mg | 3 mL | ~33.3 mg/mL |
| GLOW (GHK-Cu + BPC-157 + TB-500) | 70 mg | 3 mL | ~23.3 mg/mL |
| KLOW (BPC-157 + GHK-Cu + TB-500 + KPV) | 80 mg | 3 mL | ~26.7 mg/mL |
Published research
A selection of peer-reviewed and clinical literature indexed on PubMed. Provided so qualified researchers can locate the primary sources — inclusion here is not a claim about any product or outcome.
- Lab / formulation studyPharmaceutics · 2023
GHK-Cu tripeptide in liposomes — cosmetic study
View on PubMed - Lab / formulation studyColloids and surfaces. B, Biointerfaces · 2025
GHK-Cu microsphere filler — anti-inflammatory study
View on PubMed - Lab / formulation studyMolecules (Basel, Switzerland) · 2025
GHK-Cu skin permeation in liposomes
View on PubMed - Peer-reviewed studyRedox biology · 2024
GHK-Cu and lung inflammation / fibrosis
View on PubMed - Animal-model studyJournal of orthopaedic research : official publication of the Orthopaedic Research Society · 2015
GHK-Cu and ACL healing — rat model
View on PubMed - Peer-reviewed studyOxidative medicine and cellular longevity · 2012
GHK-Cu, oxidative stress & aging
View on PubMed - Peer-reviewed studyInternational journal of molecular sciences · 2020
GHK copper-peptide complex — chemistry study
View on PubMed - Animal-model studyLife sciences · 2020
GHK-Cu and pulmonary fibrosis — animal model
View on PubMed - Lab / formulation studyBiomaterials research · 2025
Copper-tripeptide hydrogel and wound healing
View on PubMed - Lab / formulation studyBiomolecules · 2020
Recombinant GHK tripeptide and copper toxicity — zebrafish
View on PubMed
References & resources
Related reference materials
VNG Research Team
VNG Labs supplies analytical-grade reference materials with lot-matched Certificates of Analysis. Our write-ups are neutral, source-cited references for qualified and independent researchers.
More from the research blogResearch use only. Not for human consumption or veterinary use. Sold exclusively to qualified researchers for in vitro and laboratory research. These statements have not been evaluated by the FDA. Not intended to diagnose, treat, cure, or prevent any disease. Refrigerate upon receipt. Keep in dark environment.
